View Megaloblastic Anemia Hypercellular Bone Marrow Pics. Megaloblastic anemia clinical features • fatigue, shortness of breath, weakness • destruction of posterior and lateral columns in the spinal cord—results in a loss of the senses of vibration and proprioception, as well as loss of the deep tendon reflexes • treatment vitamin b12 injections or folic. Bone marrow core biopsy and aspirate show hypercellular marrow with erythroid hyperplasia:
Histopathology images of Megaloblastic anemia by PathPedia ... from www.pathpedia.com Megaloblastic anemia develops insidiously and may not cause symptoms until anemia is severe. Hypercellular with inreased erythropoiesis, which usually dominates (m:e ratio is lower than 1:1). In moderate to severe cases, the marrow is almost always hypercellular with brisk erythroid hyperplasia (small black arrows).
Bone marrow in a treated female f344/n rat from a subchronic study.
Anemia caused by a deficiency in vitamin b12 or folate. Megaloblastic anemia is a type of anemia characterized by very large red blood cells. Megaloblastic anemia also known as macrocytic anemia, is a disorder of the bone marrow characterized by ineffective hematopoiesis, frequently manifested by reduction in the number of mature healthy red blood cells as well as the presence of unusually large. Describe the diagnosis of megaloblastic anemia in terms of hct,/wbc/platets.
